ncRNA name | hsa-miR-122 |
ncRNA Category | miRNA |
Disease name | pterygium |
Species | Homo sapiens |
Tissues/Cell_line | pterygium tissue, normal conjunctival tissue |
Methods | microarray, qRT-PCR, immunohistochemistry, transfection, luciferase reporter assay, Western blot, caspase 3/7 activity assay |
Expression pattern | down-regulated |
Functional description | Decreased expression of miR-122 in pterygium might result in abnormal cell apoptosis via its regulation of the expression of Bcl-w, and subsequently contribute to the development of pterygium. |
PubMed ID | 27415790 |
Year | 2016 |
Title | Regulation of Apoptosis by miR-122 in Pterygium via Targeting Bcl-w. |
Drug-related ncRNA | NO |
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