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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of pterygium
ncRNA name hsa-miR-122
ncRNA Category miRNA
Disease name pterygium
Species Homo sapiens
Tissues/Cell_line pterygium tissue, normal conjunctival tissue
Methods microarray, qRT-PCR, immunohistochemistry, transfection, luciferase reporter assay, Western blot, caspase 3/7 activity assay
Expression pattern down-regulated
Functional description Decreased expression of miR-122 in pterygium might result in abnormal cell apoptosis via its regulation of the expression of Bcl-w, and subsequently contribute to the development of pterygium.
PubMed ID 27415790
Year 2016
Title Regulation of Apoptosis by miR-122 in Pterygium via Targeting Bcl-w.
Drug-related ncRNA NO

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